Publisher Correction: npj Biosensing, volume 1, missing Data Availability statements
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This review covers advancements in biosensing, biophotovoltaics, and photobiomodulation, focusing on the synergistic use of light, biomaterials, cells or tissues, interfaced with photosensitive dye-sensitized, perovskite, and conjugated polymer organic semiconductors or nanoparticles. Integration of semiconductor and biological systems, using non-invasive light-probes or -stimuli for both sensing and controlling biological behavior, has led to groundbreaking applications like artificial retinas. From fusion of photovoltaics and biology, a new research field emerges: photovoltaic bioelectronics.
Biomolecule sensors based on organic electrochemical transistors
Biosensors based on organic electrochemical transistors (OECTs) have been a research highlight in recent years owing to their remarkable biocompatibility, low operating voltage, and substantial signal amplification capability. Especially, as an emerging fundamental device for biosensing, OECTs show great potential for pH, ions, molecules, and biomarker sensing. This review highlights the research progress of biomolecule sensors based on OECTs, focusing on recent publications in the past 5 years. Specifically, OECT-based biomolecule sensors for small molecules (glucose, dopamine, lactate, etc. that act as signals or effectors), and macromolecules (DNA, RNA, proteins, etc. that are often used as markers in physiology and medicine), are summarized. Additionally, emerging technologies and materials used to enhance sensitivity, detection limits, and detection ranges are described comprehensively. Last, aspects of OECT-based biomolecule sensors that need further improvement are discussed along with future opportunities and challenges.
International consensus guidelines on the implementation and monitoring of vosoritide therapy in individuals with achondroplasia
Achondroplasia is the most common genetic form of short-limbed skeletal dysplasia (dwarfism). Clinical manifestations and complications can affect individuals across the lifespan, including the need for adaptations for activities of daily living, which can affect quality of life. Current international guidelines focus on symptomatic management, with little discussion regarding potential medication, as therapeutic options were limited at the time of their publication. Vosoritide is the first pharmacological, precision treatment for achondroplasia; it was approved for use in 2021, creating a need for vosoritide treatment guidelines to support clinicians. An international collaborative of leading experts and patient advocates was formed to develop this Consensus Statement. The group developed the guideline scope and topics during a hybrid meeting in November 2023; guideline statements were subsequently ratified via Delphi methodology using a predefined consensus threshold. These statements provide recommendations across the treatment pathway, from starting treatment with vosoritide through ongoing monitoring and evaluation, to stopping vosoritide and ongoing monitoring following cessation. These guidelines recommend a minimum set of requirements and a practical framework for professionals and health services worldwide regarding the use of vosoritide to treat infants, children and young people with achondroplasia. This Consensus Statement is a supplement to already established consensus guidelines for management and care of individuals with achondroplasia.
Editorial: Breaking the silence – the launch of npj Acoustics
Introduction Sound “is one of the subtilest pieces of nature” wrote Francis Bacon in his Sylva Sylvarum in 16271. More than two centuries later Hermann…
Interracial contact shapes racial bias in the learning of person-knowledge
During impression formation, perceptual cues facilitate social categorization while person-knowledge can promote individuation and enhance person memory. Although there is extensive literature on the cross-race recognition deficit, observed when racial ingroup faces are recognized more than outgroup faces, it is unclear whether a similar deficit exists when recalling individuating information about outgroup members. To better understand how perceived race can bias person memory, the present study examined how self-identified White perceivers’ interracial contact impacts learning of perceptual cues and person-knowledge about perceived Black and White others over five sessions of training. While person-knowledge facilitated face recognition accuracy for low-contact perceivers, face recognition accuracy did not differ for high-contact perceivers based on person-knowledge availability. The results indicate a bias towards better recall of ingroup person knowledge, which decreased for high-contact perceivers across the five-day training but simultaneously increased for low-contact perceivers. Overall, the elimination of racial bias in recall of person-knowledge among high-contact perceivers amid a persistent cross-race deficit in face recognition suggests that contact may have a greater impact on the recall of person-knowledge than on face recognition.
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