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Improved linear growth after routine zinc supplementation in preterm very low birth weight infants
This study was designed (1) to compare growth, morbidity and mortality in < 33-week gestational age (GA) (very preterm, VPT) or very low birth weight (BW < 1500 grams, VLBW) infants before (Epoch-1) and after implementing routine enteral zinc (Zn) supplementation (Epoch-2) to meet recommendations, and (2) to assess serum Zn levels and associated variables.
Bioremoval of lead (pb) salts from synbiotic milk by lactic acid bacteria
The present study investigated the effects of five species of indigenous probiotic bacteria (Lactobacillus sp. and Bifidobacterium sp.) and prebiotic inulin on the decontamination of two Pb2+ salts (lead nitrate and lead acetate) in food models (low-fat, semi-fat, and high-fat milk). The average of the lowest and highest pH values was related to samples containing L. paracasei and L. acidophilus bacteria, as determined by pH change results. In most instances, adding inulin accelerated the pH-decreasing process, but the results were not particularly significant (p < 0.05). All probiotic strains were able to remove both forms of Pb salts, however, lead nitrate mitigation was significantly higher (p < 0.05). According to decontamination analysis, B. lactis was a native probiotic species with a high capacity for the absorption and biological elimination of Pb salts from milk medium (in low-, semi-, and high-fat milk, 94.41, 98.13, and 98.12% respectively). Except for low-fat milk, samples containing inulin showed greater Pb removal in semi-fat and high-fat milk than those without inulin. The findings of FTIR-ATR spectroscopy revealed that hydroxyl (OH), carbonyl (C = O), carboxylic (–COOH), phosphate (P = O), amine (–NH2), and amide (–C(= O) = N) functional groups are efficient in the absorption of Pb salts through electrostatic interactions on the cell surfaces of probiotics. The findings of this research highlighted the importance of using probiotic strains specific to the B. lactis BIA-6 species for those who are at risk of being exposed to Pb salts and other toxic components through diet.
Golden hour management of infants with congenital diaphragmatic hernia: 15 year experience at a high-volume center
To review the evolution of golden hour management and outcomes for infants with congenital diaphragmatic hernia (CDH).
Young infants’ exposure to parabens: lotion use as a potential source of exposure
Parabens are widely used as antimicrobials in personal care products and pharmaceuticals. While previous studies demonstrate paraben exposure is ubiquitous, data investigating infants’ exposure is limited.
Neonatal microbiome in the multiomics era: development and its impact on long-term health
The neonatal microbiome has been the focus of considerable research over the past two decades and studies have added fascinating information in terms of early microbial patterns and how these relate to various disease processes. One difficulty with the interpretation of these relationships is that such data is associative and provides little in terms of proof of causality or the underpinning mechanisms. Integrating microbiome data with other omics such as the proteome, inflammatory mediators, and the metabolome is an emerging approach to address this gap. Here we discuss these omics, their integration, and how they can be applied to improve our understanding, treatment, and prevention of disease.
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