Progressively differentiated TFH13 cells are stabilized by JunB to mediate allergen germinal center responses
Allergic diseases are common and affect a large proportion of the population. Interleukin-13 (IL-13)-expressing follicular helper T (TFH…
Category: Acute inflammation
Safer non-viral DNA delivery using lipid nanoparticles loaded with endogenous anti-inflammatory lipids
The value of lipid nanoparticles (LNPs) for delivery of messenger RNA (mRNA) was demonstrated by the coronavirus disease 2019 (COVID-19) mRNA vacci…
The ability of microRNAs to regulate the immune response in ischemia/reperfusion inflammatory pathways
MicroRNAs play a crucial role in regulating the immune responses induced by ischemia/reperfusion injury. Through their ability to modulate gene exp…
Immune pathogenic response landscape of acute posterior multifocal placoid pigment epitheliopathy revealed by scRNA sequencing
Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is an exceptionally rare inflammatory disorder affecting choroid and retinal pig…
Lipid metabolism-related genes are involved in the formation of macrophage extracellular traps in allergic airway inflammation
Recent studies have highlighted the critical role of lipid metabolism in macrophages concerning lung inflammation. However, it remains unclear whet…
Annexin A1 regulates inflammatory-immune response and reduces pancreatic and extra- pancreatic injury during severe acute pancreatitis
Severe acute pancreatitis (SAP) poses significant challenges due to its complex pathophysiology, which includes inflammatory-immune responses that …
Gut-derived macrophages link intestinal damage to brain injury after cardiac arrest through TREM1 signaling
Brain injury is the leading cause of death and disability in survivors of cardiac arrest, where neuroinflammation triggered by infiltrating macroph…
Tenascin-C promotes bone regeneration via inflammatory macrophages
During the early stage of tissue injury, macrophages play important roles in the activation of stem cells for further regeneration. However, the re…