A historical perspective on the multifunctional outer membrane channel protein TolC in Escherichia coli
Since its discovery nearly 60 years ago, TolC has been associated with various cellular functions in Escherichia coli, including the efflux …
Category: Bacteria
Epidemiology, mechanisms, and clinical impact of bacterial heteroresistance
Bacterial heteroresistance, a phenomenon where subpopulations within a bacterial strain exhibit significantly reduced antibiotic susceptibility com…
Innovative perspectives on the discovery of small molecule antibiotics
Antibiotics are essential to modern medicine, but multidrug-resistant (MDR) bacterial infections threaten their efficacy. Resistance evolution shor…