Guillain–Barré syndrome
Guillain–Barré syndrome (GBS) is a rare immune-mediated polyradiculoneuropathy. Patients typically develop rapidly progressive weakness and sens…
Category: Autoimmunity
B cell immunometabolism in health and disease
B cells have crucial roles in the initiation and progression of many pathological conditions, and several therapeutic strategies have targeted the …
The shared role of neutrophils in ankylosing spondylitis and ulcerative colitis
This study aimed to analyze single-cell sequencing data to investigate immune cell interactions in ankylosing spondylitis (AS) and ulcerative colit…
Identification of the ferroptosis‐related gene signature and the associated regulation axis in lung cancer and rheumatoid arthritis
Patients with Rheumatoid arthritis (RA) have an elevated risk of lung cancer compared to the healthy population. However, there are few studies on …
Innate immune dynamics in the context of multisite EGFR mutations in lung adenocarcinoma
Based on favorable outcomes and decreased propensity for lymph node and distant metastasis, multiple ground-glass nodules (GGNs) are now predominan…
Regulatory T cells-related gene in primary sclerosing cholangitis: evidence from Mendelian randomization and transcriptome data
The present study utilized large-scale genome-wide association studies (GWAS) summary data (731 immune cell subtypes and three primary sclerosing c…
Roles of TULA-family proteins in T cells and autoimmune diseases
The T cell Ubiquitin Ligand (TULA) protein family contains two members, UBASH3A and UBASH3B, that display similarities in protein sequence and doma…
The need for Cre-loci controls in conditional mouse experiments: Mrp8-cre transgene predisposes mice to antibody-induced arthritis
The Cre/loxP system is extensively utilized to pinpoint gene functions in specific cell types or developmental stages, typically without major dist…