Autophagy and hepatic lipid metabolism: mechanistic insight and therapeutic potential for MASLD
Metabolic dysfunction-associated steatotic liver disease (MASLD) originates from a homeostatic imbalance in hepatic lipid metabolism. Increased fat…
Category: Cell biology
Pulling back the mitochondria’s iron curtain
Mitochondrial functionality and cellular iron homeostasis are closely intertwined. Mitochondria are biosynthetic hubs for essential iron cofactors …
Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties
Cells secrete a large variety of extracellular vesicles (EVs) to engage in cell-to-cell and cell-to-environment intercellular communication. EVs ar…
Insights from lipidomics into the terminal maturation of circulating human reticulocytes
In the age of “omics”, lipidomics of erythropoiesis is still missing. How reticulocytes mature in the circulation into functional erythrocytes …