Synergistic protection of nascent DNA at stalled forks by MSANTD4 and BRCA1/2–RAD51
The regressed arms of reversed replication forks exhibit structural similarities to one-ended double-stranded breaks and need to be protected again…
Category: Cell signalling
Plasma membrane-associated ARAF condensates fuel RAS-related cancer drug resistance
RAF protein kinases are major RAS effectors that function by phosphorylating MEK. Although all three RAF isoforms share a conserved RAS binding dom…