Homeostasis control in health and disease by the unfolded protein response
Cells rely on the endoplasmic reticulum (ER) to fold and assemble newly synthesized transmembrane and secretory proteins — essential for cellular…
Category: Cell biology
Comprehensive discovery and functional characterization of the noncanonical proteome
The systematic identification and functional characterization of noncanonical translation products, such as novel peptides, will facilitate the und…
Apoptotic priming in senescence predicts specific senolysis by quantitative analysis of mitochondrial dependencies
Cellular senescence contributes to a variety of pathologies associated with aging and is implicated as a cellular state in which cancer cells can s…
Identification of increased dedifferentiation along the Prom1+ cancer cells in Müllerian adenosarcoma with sarcomatous overgrowth
Müllerian adenosarcoma (MA) is a rare tumour accounts for 5–7% of uterine sarcomas. Tumours with sarcomatous overgrowth (MASO) or high-grade ten…