Adapting systems biology to address the complexity of human disease in the single-cell era
Systems biology aims to achieve holistic insights into the molecular workings of cellular systems through iterative loops of measurement, analysis …
Category: Functional genomics
Functional analysis of cancer-associated germline risk variants
Single-nucleotide variants (SNVs) in regulatory DNA are linked to inherited cancer risk. Massively parallel reporter assays of 4,041 SNVs linked to…