High-resolution imaging of plasma membrane proteins
Category: Cryoelectron microscopy
Structural mechanism underlying PHO1;H1-mediated phosphate transport in Arabidopsis
Arabidopsis PHOSPHATE 1 (AtPHO1) and its closest homologue AtPHO1;H1 are phosphate transporters that load phosphate into the xylem vessel fo…
The structural basis for the human procollagen lysine hydroxylation and dual-glycosylation
The proper assembly and maturation of collagens necessitate the orchestrated hydroxylation and glycosylation of multiple lysyl residues in procolla…
Structural basis for intrinsic strand displacement activity of mitochondrial DNA polymerase
Members of the Pol A family of DNA polymerases, found across all domains of life, utilize various strategies for DNA strand separation during repli…
Structural insights into spliceosome fidelity: DHX35–GPATCH1- mediated rejection of aberrant splicing substrates
The spliceosome, a highly dynamic macromolecular assembly, catalyzes the precise removal of introns from pre-mRNAs. Recent studies have provided co…
Cryo-EM structure of PML RBCC dimer reveals CC-mediated octopus-like nuclear body assembly mechanism
Promyelocytic leukemia protein (PML) nuclear bodies (NBs) are essential in regulating tumor suppression, antiviral response, inflammation, metaboli…