Proline exacerbates hepatic gluconeogenesis via paraspeckle-dependent mRNA retention
Type 2 diabetes (T2D) is a global health issue characterized by abnormal blood glucose levels and is often associated with excessive hepatic glucon…
Category: Glycobiology
Growth factor-triggered de-sialylation controls glycolipid-lectin-driven endocytosis
Glycolipid-lectin-driven endocytosis controls the formation of clathrin-independent carriers and the internalization of various cargos such as β1 …
Crosstalk between O-GlcNAcylation and phosphorylation in metabolism: regulation and mechanism
Cells produce metabolic intermediates through catalytic reactions, mainly via post-translational modifications. The modification of proteins by O-l…