Category: Therapeutics

Steps forward in the treatment of IgA nephropathy

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Structure and function of a broad-range thermal receptor in myriapods
Local structural flexibility drives oligomorphism in computationally designed protein assemblies
Cryo-EM structure of the human THIK-1 K2P K+ channel reveals a lower Y gate regulated by lipids and anesthetics
Structures of a natural circularly permuted group II intron reveal mechanisms of branching and backsplicing
A PAR6–aPKC–LGL structure reveals how LGL antagonizes aPKC