Ion channel traffic jams: the significance of trafficking deficiency in long QT syndrome
A well-balanced ion channel trafficking machinery is paramount for the normal electromechanical function of the heart. Ion channel variants and man…
Category: Mechanisms of disease
Historical loss weakens competitive behavior by remodeling ventral hippocampal dynamics
Competitive interactions are pervasive within biological populations, where individuals engage in fierce disputes over vital resources for survival…
Targeting MDM2 affects spastin protein levels and functions: implications for HSP treatment
Spastin is a microtubule (MT) severing enzyme that regulates several cell functions associated with MT dynamics. A reduction in spastin protein lev…
Endothelial senescence induced by PAI-1 promotes endometrial fibrosis
Intrauterine adhesions (IUAs), also known as Asherman’s syndrome (AS), represent a significant cause of uterine infertility for which effective t…