Latent circuit inference from heterogeneous neural responses during cognitive tasks
Higher cortical areas carry a wide range of sensory, cognitive and motor signals mixed in heterogeneous responses of single neurons tuned to multip…
Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time
Events occurring close in time are often linked in memory, and recent studies suggest that such memories are encoded by overlapping neuronal ensemb…
Brain pericytes and perivascular fibroblasts are stromal progenitors with dual functions in cerebrovascular regeneration after stroke
Functional revascularization is key to stroke recovery and requires remodeling and regeneration of blood vessels around which is located the brain�…
Hippocampus shapes entorhinal cortical output through a direct feedback circuit
Our brains integrate sensory, cognitive and internal state information with memories to extract behavioral relevance. Cortico–hippocampal interac…
Developmentally distinct architectures in top–down pathways controlling threat avoidance
The medial prefrontal cortex (mPFC) is critical for learning and decision-making processes, including responding to threats. The protracted maturat…
Astrocyte heterogeneity reveals region-specific astrogenesis in the white matter
Astrocyte heterogeneity has been well explored, but our understanding of white matter (WM) astrocytes and their distinctions from gray matter (GM) …
Distinct effects of early-stage and late-stage socioeconomic factors on brain and behavioral traits
Socioeconomic status (SES) is a time-varying multidimensional construct with ill-defined dimension-specific and age-specific effects on brain and b…
PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors
Enlargement of the cerebrospinal fluid (CSF)-filled brain ventricles (ventriculomegaly) is a defining feature of congenital hydrocephalus (CH) and …
Neuronal polyunsaturated fatty acids are protective in ALS/FTD
Here we report a conserved transcriptomic signature of reduced fatty acid and lipid metabolism gene expression in a Drosophila model of C…