Enhancing immunity during ageing by targeting interactions within the tissue environment
Immunity declines with age. This results in a higher risk of age-related diseases, diminished ability to respond to new infections and reduced resp…
Tag: Adaptive immunity
Biological and clinical significance of tumour-infiltrating lymphocytes in the era of immunotherapy: a multidimensional approach
Immune-checkpoint inhibitors (ICIs) have improved clinical outcomes across several solid tumour types. Prominent efforts have focused on understand…
Haematometabolism rewiring in atherosclerotic cardiovascular disease
Atherosclerotic cardiovascular diseases are the most frequent cause of death worldwide. The clinical complications of atherosclerosis are closely l…
Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity
Metastasis is the spread of cancer cells from primary tumours to distant organs and is the cause of 90% of cancer deaths globally1,2. Me…