Integrons are anti-phage defence libraries in Vibrio parahaemolyticus
Bacterial genomes have regions known as defence islands that encode diverse systems to protect against phage infection. Although genetic elements t…
Tag: Bacteriophages
Sustained in situ protein production and release in the mammalian gut by an engineered bacteriophage
Oral administration of biologic drugs is challenging because of the degradative activity of the upper gastrointestinal tract. Strategies that use e…
Enhancing phage therapy by coating single bacteriophage-infected bacteria with polymer to preserve phage vitality
The efficacy of bacteriophages in treating bacterial infections largely depends on the phages’ vitality, which is impaired when they are naturall…
Simultaneous entry as an adaptation to virulence in a novel satellite-helper system infecting Streptomyces species
Satellites are mobile genetic elements that are dependent upon the replication machinery of their helper viruses. Bacteriophages have provided many…
Widespread and largely unknown prophage activity, diversity, and function in two genera of wheat phyllosphere bacteria
Environmental bacteria host an enormous number of prophages, but their diversity and natural functions remain largely elusive. Here, we investigate…
Ubiquitous, B12-dependent virioplankton utilizing ribonucleotide-triphosphate reductase demonstrate interseasonal dynamics and associate with a diverse range of bacterial hosts in the pelagic ocean
Through infection and lysis of their coexisting bacterial hosts, viruses impact the biogeochemical cycles sustaining globally significant pelagic o…
Contrasting drivers of abundant phage and prokaryotic communities revealed in diverse coastal ecosystems
Phages (viruses of bacteria and archaea) are a ubiquitous top-down control on microbial communities by selectively infecting and killing cells. As …