Multi-omics approaches to decipher the interactions of nanoparticles and biological systems
Understanding how engineered nanoparticles interact with biological systems is crucial for the development and implementation of nanoparticles in c…
Tag: Bioinformatics
Mapping T cell dynamics to molecular profiles through behavior-guided transcriptomics
The rise of cellular immunotherapy for cancer treatment has led to the utilization of immune oncology cocultures to simulate T cell interactions wi…
A guide to reverse metabolomics—a framework for big data discovery strategy
Untargeted metabolomics is evolving into a field of big data science. There is a growing interest within the metabolomics community in mining tande…
Metagenomic estimation of dietary intake from human stool
Dietary intake is tightly coupled to gut microbiota composition, human metabolism and the incidence of virtually all major chronic diseases. Dietar…
A unified deep framework for peptide–major histocompatibility complex–T cell receptor binding prediction
Antigen peptides that are presented by a major histocompatibility complex (MHC) and recognized by a T cell receptor (TCR) have an essential role in…
The genome sequence of the Violet Carpenter Bee, Xylocopa violacea (Linnaeus, 1785): a hymenopteran species undergoing range expansion
We present a reference genome assembly from an individual male Violet Carpenter Bee (Xylocopa violacea, Linnaeus 1758). The assembly is 1.02…
Stem cell transplantation extends the reproductive life span of naturally aging cynomolgus monkeys
The ovary is crucial for female reproduction and health, as it generates oocytes and secretes sex hormones. Transplantation of mesenchymal stem cel…
Characterization of the landscape of the intratumoral microbiota reveals that Streptococcus anginosus increases the risk of gastric cancer initiation and progression
As a critical component of the tumour immune microenvironment (TIME), the resident microbiota promotes tumorigenesis across a variety of cancer typ…