Tag: Biomarkers
Distinct effects of early-stage and late-stage socioeconomic factors on brain and behavioral traits
Socioeconomic status (SES) is a time-varying multidimensional construct with ill-defined dimension-specific and age-specific effects on brain and b…
Large-scale multi-omics identifies drug targets for heart failure with reduced and preserved ejection fraction
Heart failure (HF) has limited therapeutic options. In this study, we differentiated the pathophysiological underpinnings of the HF subtypes—HF w…
Soluble cerebral Aβ protofibrils link Aβ plaque pathology to changes in CSF Aβ42/Aβ40 ratios, neurofilament light and tau in Alzheimer’s disease model mice
The Aβ42/Aβ40 ratio in the cerebrospinal fluid (CSF) and the concentrations of neurofilament light (NfL) and total tau (t-t…
Morphological alterations of the thymus gland in individuals with schizophrenia
Despite its critical function in the immune system and accumulating evidence of immunological abnormalities in schizophrenia, the thymus has long b…
Cuproptosis-related lncRNA JPX regulates malignant cell behavior and epithelial-immune interaction in head and neck squamous cell carcinoma via miR-193b-3p/PLAU axis
The development, progression, and curative efficacy of head and neck squamous cell carcinoma (HNSCC) are influenced by complex interactions between…