Artificial intelligence in digital pathology — time for a reality check
The past decade has seen the introduction of artificial intelligence (AI)-based approaches aimed at optimizing several workflows across many medica…
Tag: Cancer imaging
Imaging-guided precision hyperthermia with magnetic nanoparticles
Magnetic nanoparticles, including those formed of superparamagnetic iron oxides (SPIOs), are employed in various magnetic imaging and therapeutic t…
Mapping T cell dynamics to molecular profiles through behavior-guided transcriptomics
The rise of cellular immunotherapy for cancer treatment has led to the utilization of immune oncology cocultures to simulate T cell interactions wi…
Imaging of cellular dynamics from a whole organism to subcellular scale with self-driving, multiscale microscopy
Most biological processes, from development to pathogenesis, span multiple time and length scales. While light-sheet fluorescence microscopy has be…
GenAI synthesis of histopathological images from Raman imaging for intraoperative tongue squamous cell carcinoma assessment
The presence of a positive deep surgical margin in tongue squamous cell carcinoma (TSCC) significantly elevates the risk of local recurrence. There…
Swarm learning with weak supervision enables automatic breast cancer detection in magnetic resonance imaging
Over the next 5 years, new breast cancer screening guidelines recommending magnetic resonance imaging (MRI) for certain patients will significantly…
The radiogenomic and spatiogenomic landscapes of glioblastoma and their relationship to oncogenic drivers
Glioblastoma is a highly heterogeneous brain tumor, posing challenges for precision therapies and patient stratification in clinical trials. Unders…
Intratumoral and peritumoral PET/CT-based radiomics for non-invasively and dynamically predicting immunotherapy response in NSCLC
We aimed to develop a machine learning model based on intratumoral and peritumoral 18F-FDG PET/CT radiomics to non-invasively and dynami…
Potentiation of immune checkpoint blockade with a pH-sensitizer as monitored in two pre-clinical tumor models with acidoCEST MRI
Tumor acidosis causes resistance to immune checkpoint blockade (ICB). We hypothesized that a “pH-sensitizer” can increase tumor extracellular p…