Systemic capillary leak syndrome
The vascular endothelial barrier maintains intravascular volume and metabolic homeostasis. Although plasma fluids and proteins extravasate continuo…
Tag: Cardiovascular diseases
Hereditary haemorrhagic telangiectasia
Hereditary haemorrhagic telangiectasia (HHT) is a vascular dysplasia inherited as an autosomal dominant trait and caused by loss-of-function pathog…
Functional diversity of cardiac macrophages in health and disease
Macrophages make up a substantial portion of the stromal compartment of the heart in health and disease. In the past decade, the origins of these c…
The spleen in ischaemic heart disease
Ischaemic heart disease is a consequence of coronary atherosclerosis, and atherosclerosis is a systemic inflammatory disease. The spleen releases v…
The relationship between cannabis and cardiovascular disease: clearing the haze
Cannabis has been consumed for centuries, but global regulatory changes over the past three decades have increased the availability and consumption…
Roadmap for alleviating the manifestations of ageing in the cardiovascular system
Ageing of the cardiovascular system is associated with frailty and various life-threatening diseases. As global populations grow older, age-related…
Endomyocardial fibrosis: recent advances and future therapeutic targets
Endomyocardial fibrosis, first described >75 years ago, is a cause of restrictive cardiomyopathy with an unclear aetiopathogenesis that is most …