Author Correction: Engineering a DNA polymerase for modifying large RNA at specific positions
Tag: Chemical modification
A DNA phosphorothioation pathway via adenylated intermediate modulates Tdp machinery
In prokaryotes, the non-bridging oxygen in the DNA sugar-phosphate backbone can be enzymatically replaced by a sulfur atom, resulting in phosphorot…
Internal cap-initiated translation for efficient protein production from circular mRNA
Circular mRNA faces challenges in enhancing its translation potential as an RNA therapeutic. Here we introduce two molecular designs that bolster c…
Chemical reactivity of RNA and its modifications with hydrazine
RNA modifications are essential for the regulation of cellular processes and have a key role in diseases such as cancer and neurological disorders.…
Isoaspartate-containing galanin in rat hypothalamus
The isoaspartate residue is a spontaneous, time-dependent post-translational modification (PTM) of proteins and peptides, associated with in vivo p…