Beyond bacteria: Phanta adds flavour to microbiome profiling with a focus on phages
Tag: Computational biology and bioinformatics
Multiomic single-cell profiling identifies critical regulators of postnatal brain
Human brain development spans from embryogenesis to adulthood, with dynamic gene expression controlled by cell-type-specific cis-regulatory …
Secure and federated genome-wide association studies for biobank-scale datasets
Sharing data across institutions for genome-wide association studies (GWAS) would enhance the discovery of genetic variation linked to health and d…
The transcriptomic architecture of common cancers reflects synthetic lethal interactions
To maintain cell fitness, deleterious genetic alterations are buffered by compensatory changes in additional genes. In cancer, buffering processes …
Chimeric origins and dynamic evolution of central carbon metabolism in eukaryotes
The origin of eukaryotes was a key event in the history of life. Current leading hypotheses propose that a symbiosis between an asgardarchaeal host…