Topological interactions drive the first fate decision in the Drosophila embryo
During embryogenesis, the first cell fate decision—whether the cell participates in development of the embryo or not—is often linked to the pos…
Tag: Computational biophysics
Mechanochemical bistability of intestinal organoids enables robust morphogenesis
Reproducible pattern and form generation during embryogenesis is poorly understood. Intestinal organoid morphogenesis involves a number of mechanoc…
Imaging of cellular dynamics from a whole organism to subcellular scale with self-driving, multiscale microscopy
Most biological processes, from development to pathogenesis, span multiple time and length scales. While light-sheet fluorescence microscopy has be…