Generation of human fetal brain organoids and their CRISPR engineering for brain tumor modeling
The developing human brain displays unique features that are difficult to study in animal models. Current in vitro models based on human brain tiss…
Tag: Developmental neurogenesis
PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors
Enlargement of the cerebrospinal fluid (CSF)-filled brain ventricles (ventriculomegaly) is a defining feature of congenital hydrocephalus (CH) and …