Progress in understanding the vertebrate segmentation clock
The segmentation clock is a molecular oscillator that regulates the periodic formation of somites from the presomitic mesoderm during vertebrate em…
Tag: Differentiation
Direct specification of lymphatic endothelium from mesenchymal progenitors
During embryogenesis, endothelial cells (ECs) are generally described to arise from a common pool of progenitors termed angioblasts, which diversif…
CREB3L1 deficiency impairs odontoblastic differentiation and molar dentin deposition partially through the TMEM30B
Odontoblasts are primarily responsible for synthesizing and secreting extracellular matrix proteins, which are crucial for dentinogenesis. Our prev…
Pancreatic organogenesis mapped through space and time
The spatial organization of cells within a tissue is dictated throughout dynamic developmental processes. We sought to understand whether cells geo…