Tag: Diseases of the nervous system
Microglia dysfunction, neurovascular inflammation and focal neuropathologies are linked to IL-1- and IL-6-related systemic inflammation in COVID-19
COVID-19 is associated with diverse neurological abnormalities, but the underlying mechanisms are unclear. We hypothesized that microglia, the resi…
Spotiphy enables single-cell spatial whole transcriptomics across an entire section
Spatial transcriptomics (ST) has advanced our understanding of tissue regionalization by enabling the visualization of gene expression within whole…
Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity
Dysfunctions in autophagy, a cellular mechanism for breaking down components within lysosomes, often lead to neurodegeneration. The specific mechan…
Challenges and opportunities of acquiring cortical recordings for chronic adaptive deep brain stimulation
Deep brain stimulation (DBS), a proven treatment for movement disorders, also holds promise for the treatment of psychiatric and cognitive conditio…
Altered gray matter structural covariance networks in young adults with obesity
Overwhelming evidence showed that obesity was associated with abnormal brain functional networks. However, the changes of structural covariance net…
Accelerated symptom improvement in Parkinson’s disease via remote internet-based optimization of deep brain stimulation therapy: a randomized controlled multicenter trial
Deep brain stimulation (DBS) has emerged as an important therapeutic intervention for neurological and neuropsychiatric disorders. After initial pr…