Bioengineering embryo models
Stem cell-based embryo models, which recapitulate symmetry breaking, pattern formation and tissue morphogenesis during early development, provide p…
Tag: Embryogenesis
Imaging of cellular dynamics from a whole organism to subcellular scale with self-driving, multiscale microscopy
Most biological processes, from development to pathogenesis, span multiple time and length scales. While light-sheet fluorescence microscopy has be…
Coupling of cell shape, matrix and tissue dynamics ensures embryonic patterning robustness
Tissue patterning coordinates morphogenesis, cell dynamics and fate specification. Understanding how precision in patterning is robustly achieved d…
Melatonin affects trophoblast epithelial-to-mesenchymal transition and oxidative damage resistance by modulating GDF15 expression to promote embryo implantation
Melatonin is widely observed in the female reproductive system and regulates trophoblast cell functions, but its effects on embryo implantation and…
Sirt6 loss activates Got1 and facilitates cleft palate through abnormal activating glycolysis
Cleft palate (CP) is a common congenital craniofacial malformation, which is caused by a combination of genetic and environmental factors. However,…