Tag: End-stage renal disease
Risk-directed management of chronic kidney disease
The timely and rational institution of therapy is a key step towards reducing the global burden of chronic kidney disease (CKD). CKD is a heterogen…
Advances and challenges in kidney fibrosis therapeutics
Chronic kidney disease (CKD) is a major global health burden that affects more than 10% of the adult population. Current treatments, including dial…
End-stage ADPKD with a low-frequency PKD1 mosaic variant accelerated by chemoradiotherapy
Autosomal dominant polycystic kidney disease (ADPKD) is commonly caused by PKD1, and mosaic PKD1 variants result in milder phenotypes…