Evolution, genetic diversity, and health
Human genetic diversity in today’s world has been shaped by evolutionary history, demographic shifts and environmental exposures, influencing com…
Tag: Evolutionary genetics
Evolutionary divergence between homologous X–Y chromosome genes shapes sex-biased biology
Sex chromosomes are a fundamental aspect of sex-biased biology, but the extent to which homologous X–Y gene pairs (‘the gametologs’) contribu…
Macroevolution along developmental lines of least resistance in fly wings
Evolutionary change requires genetic variation, and a reigning paradigm in biology is that rates of microevolution can be predicted from estimates …
Origin and stepwise evolution of vertebrate lungs
Lungs are essential respiratory organs in terrestrial vertebrates, present in most bony fishes but absent in cartilaginous fishes, making them an i…
Genomic and phenotypic evidence support visual and olfactory shifts in primate evolution
Sensory trade-offs between vision and olfaction in the evolution and radiation of primates have long been debated. However, insights have been limi…
Drivers of interlineage variability in mitogenomic evolutionary rates in Platyhelminthes
Studies of forces driving interlineage variability in the evolutionary rates (both sequence and architecture) of mitochondrial genomes often produc…
Stem cell transcriptional profiles from mouse subspecies reveal cis-regulatory evolution at translation genes
A key goal of evolutionary genomics is to harness molecular data to draw inferences about selective forces that have acted on genomes. The field pr…
Transitions in sex determination mechanisms through parental and sexual antagonism
Sex chromosomes carry the sex-determining locus, causing them to be differently transmitted to and from females and males. These differences lead t…
Accelerated differentiation of neo-W nuclear-encoded mitochondrial genes between two climate-associated bird lineages signals potential co-evolution with mitogenomes
There is considerable evidence for mitochondrial-nuclear co-adaptation as a key evolutionary driver. Hypotheses regarding the roles of sex-linkage …