Linking single-cell transcriptomes with secretion using SEC-seq
Cells secrete numerous proteins and other biomolecules into their surroundings to achieve critical functions—from communicating with other cells …
Tag: Gene expression profiling
Decoding heterogeneous single-cell perturbation responses
Understanding how cells respond differently to perturbation is crucial in cell biology, but existing methods often fail to accurately quantify and …
METTL7A-mediated m6A modification of corin reverses bisphosphonates-impaired osteogenic differentiation of orofacial BMSCs
Bisphosphonate-related osteonecrosis of jaw (BRONJ) is characterized by impaired osteogenic differentiation of orofacial bone marrow stromal cells …
A potential coagulation-related diagnostic model associated with immune infiltration for acute myocardial infarction
The production of pro-coagulation factors can affect the development and prognosis of acute myocardial infarction (AMI). The clinical value of coag…
LRP5 promotes adipose progenitor cell fitness and adipocyte insulin sensitivity
WNT signaling plays a key role in postnatal bone formation. Individuals with gain-of-function mutations in the WNT co-receptor LRP5 exhibit increas…