Alcohol use disorder (AUD) is highly heritable and burdensome worldwide. Genome-wide association studies can provide new evidence regarding the eti…
Depression is a risk factor for the later development of Alzheimer’s disease (AD), but evidence for the genetic relationship is mixed. Assessing …
We conducted a genome-wide association study on income among individuals of European descent (N = 668,288) to investigate the relationsh…
Deciphering the genetic architecture of depression is pivotal for characterizing the associated pathophysiological processes and development of new…
Hypertrophic cardiomyopathy (HCM) is an important cause of morbidity and mortality with both monogenic and polygenic components. Here, we report re…
Our current understanding of the determinants of plasma proteome variation during pediatric development remains incomplete. Here, we show that gene…
Sharing data across institutions for genome-wide association studies (GWAS) would enhance the discovery of genetic variation linked to health and d…
The contribution of rare noncoding genetic variation to common phenotypes is largely unknown, as a result of a historical lack of population-scale …
Heart failure (HF) is a major contributor to global morbidity and mortality. While distinct clinical subtypes, defined by etiology and left ventric…
Atrial fibrillation (AF) is the most common heart rhythm abnormality and is a leading cause of heart failure and stroke. This large-scale meta-anal…