Tag: Immunosurveillance
Integrated machine learning survival framework to decipher diverse cell death patterns for predicting prognosis in lung adenocarcinoma
Various forms of programmed cell death (PCD) collectively regulate the occurrence, development and metastasis of tumors. Nevertheless, a comprehens…
Neutrophils in cancer: from biology to therapy
The view of neutrophils has shifted from simple phagocytic cells, whose main function is to kill pathogens, to very complex cells that are also inv…
Cholesterol homeostasis and lipid raft dynamics at the basis of tumor-induced immune dysfunction in chronic lymphocytic leukemia
Autologous T-cell therapies show limited efficacy in chronic lymphocytic leukemia (CLL), where acquired immune dysfunction prevails. In CLL, distur…
The potential impact of RNA splicing abnormalities on immune regulation in endometrial cancer
RNA splicing controls the post-transcriptional level of gene expression, allowing for the synthesis of many transcripts with various configurations…