A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilience
Blood-borne factors are essential to maintain neuronal synaptic plasticity and cognitive resilience throughout life. One such factor is osteocalcin…
Tag: Macroautophagy
Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis
Cancer cells with RAS mutations exhibit enhanced autophagy, essential for their proliferation and survival, making it a potential target for therap…
Loss of TC-PTP in keratinocytes leads to increased UVB-induced autophagy
Ultraviolet B (UVB) radiation can distort cellular homeostasis and predispose the skin to carcinogenesis. Amongst the deteriorating effects of the …
RAB33A promotes metastasis via RhoC accumulation through non-canonical autophagy in cervical cancer
Cervical cancer metastasis is characterized by the systemic spread of tumor cells. However, the underlying mechanism remains incompletely understoo…
Atlas of expression of acyl CoA binding protein/diazepam binding inhibitor (ACBP/DBI) in human and mouse
Acyl CoA binding protein encoded by diazepam binding inhibitor (ACBP/DBI) is a tissue hormone that stimulates lipo-anabolic responses and inhibits …
Mechanisms of regulated cell death during plant infection by the rice blast fungus Magnaporthe oryzae
Fungi are the most important group of plant pathogens, responsible for many of the world’s most devastating crop diseases. One of the reasons the…
Redox regulation of TRIM28 facilitates neuronal ferroptosis by promoting SUMOylation and inhibiting OPTN-selective autophagic degradation of ACSL4
Ferroptosis is one of the cell death programs occurring after spinal cord injury (SCI) and is driven by iron-dependent phospholipid peroxidation. H…