Hangry hairs: intermittent fasting linked to hair loss
Tag: Mechanisms of disease
The comprehensive SARS-CoV-2 ‘hijackome’ knowledge base
The continuous evolution of SARS-CoV-2 has led to the emergence of several variants of concern (VOCs) that significantly affect global health. This…
Ion channel traffic jams: the significance of trafficking deficiency in long QT syndrome
A well-balanced ion channel trafficking machinery is paramount for the normal electromechanical function of the heart. Ion channel variants and man…
Mettl3-m6A-NPY axis governing neuron–microglia interaction regulates sleep amount of mice
Sleep behavior is regulated by diverse mechanisms including genetics, neuromodulation and environmental signals. However, it remains completely unk…
A tumor-secreted protein utilizes glucagon release to cause host wasting
Tumor‒host interaction plays a critical role in malignant tumor-induced organ wasting across multiple species. Despite known regulation of region…
Transgenerational inheritance of diabetes susceptibility in male offspring with maternal androgen exposure
Androgen exposure (AE) poses a profound health threat to women, yet its transgenerational impacts on male descendants remain unclear. Here, employi…
Historical loss weakens competitive behavior by remodeling ventral hippocampal dynamics
Competitive interactions are pervasive within biological populations, where individuals engage in fierce disputes over vital resources for survival…
Targeting MDM2 affects spastin protein levels and functions: implications for HSP treatment
Spastin is a microtubule (MT) severing enzyme that regulates several cell functions associated with MT dynamics. A reduction in spastin protein lev…