Tissue microenvironments are extremely complex and heterogeneous. It is challenging to study metabolic interaction between the different cell types…
Untargeted metabolomics is evolving into a field of big data science. There is a growing interest within the metabolomics community in mining tande…
Dysfunctions in autophagy, a cellular mechanism for breaking down components within lysosomes, often lead to neurodegeneration. The specific mechan…
Increased glycolytic flux is a hallmark of cancer; however, an increasing body of evidence indicates that glycolytic ATP production may be dispensa…
Macrophages stimulated by lipopolysaccharide (LPS) generate mitochondria-derived reactive oxygen species (mtROS) that act as antimicrobial agents a…
Lung adenocarcinoma (LUAD) is an aggressive cancer defined by oncogenic drivers and metabolic reprogramming. Here we leverage next-generation spati…