fMRI data acquisition and analysis for task-free, anesthetized rats
Templates for the acquisition of large datasets such as the Human Connectome Project guide the neuroimaging community to reproducible data acquisit…
Tag: Neural circuits
Optogenetic modulation of long-range cortical circuits in awake nonhuman primates
Causal control of short- and long-range projections between networks is necessary to study complex cognitive processes and cortical computations. N…
Laser microsurgery for presynaptic interrogation
Synaptic connections among neurons are critical for information processing and memory storage in the brain, making them hotspots for neuropathologi…
Visually guided in vivo single-cell electroporation for monitoring and manipulating mammalian hippocampal neurons
Sparse, single-cell labeling approaches enable high-resolution, high signal-to-noise recordings from subcellular compartments and intracellular org…
The developmental emergence of reliable cortical representations
The fundamental structure of cortical networks arises early in development before the onset of sensory experience. However, how endogenously genera…
A thalamic hub-and-spoke network enables visual perception during action by coordinating visuomotor dynamics
For accurate perception and motor control, an animal must distinguish between sensory experiences elicited by external stimuli and those elicited b…
Latent circuit inference from heterogeneous neural responses during cognitive tasks
Higher cortical areas carry a wide range of sensory, cognitive and motor signals mixed in heterogeneous responses of single neurons tuned to multip…
Hippocampus shapes entorhinal cortical output through a direct feedback circuit
Our brains integrate sensory, cognitive and internal state information with memories to extract behavioral relevance. Cortico–hippocampal interac…
Developmentally distinct architectures in top–down pathways controlling threat avoidance
The medial prefrontal cortex (mPFC) is critical for learning and decision-making processes, including responding to threats. The protracted maturat…
PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors
Enlargement of the cerebrospinal fluid (CSF)-filled brain ventricles (ventriculomegaly) is a defining feature of congenital hydrocephalus (CH) and …