Voltage-gated sodium channels in excitable cells as drug targets
Excitable cells — including neurons, muscle cells and cardiac myocytes — are unique in expressing high densities of voltage-gated sodium (Na
The brain–heart axis: integrative cooperation of neural, mechanical and biochemical pathways
The neural and cardiovascular systems are pivotal in regulating human physiological, cognitive and emotional states, constantly interacting through…
Fabrication of nonplanar tapered fibers to integrate optical and electrical signals for neural interfaces in vivo
Implantable multifunctional probes have transformed neuroscience research, offering access to multifaceted brain activity that was previously unatt…
Structural connectome construction using constrained spherical deconvolution in multi-shell diffusion-weighted magnetic resonance imaging
Connectional neuroanatomical maps can be generated in vivo by using diffusion-weighted magnetic resonance imaging (dMRI) data, and their representa…
DeepPrep: an accelerated, scalable and robust pipeline for neuroimaging preprocessing empowered by deep learning
Neuroimaging has entered the era of big data. However, the advancement of preprocessing pipelines falls behind the rapid expansion of data volume, …
Separate orexigenic hippocampal ensembles shape dietary choice by enhancing contextual memory and motivation
The hippocampus (HPC) has emerged as a critical player in the control of food intake, beyond its well-known role in memory. While previous studies …
An analysis on the role of glucagon-like peptide-1 receptor agonists in cognitive and mental health disorders
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are novel drugs approved for diabetes and obesity. They are acknowledged as a major scientific…
Inhibitory control of speech production in the human premotor frontal cortex
Voluntary, flexible stopping of speech output is an essential aspect of speech motor control, especially during natural conversations. The cognitiv…