Transcription regulation by biomolecular condensates
Biomolecular condensates regulate transcription by dynamically compartmentalizing the transcription machinery. Classic models of transcription regu…
Tag: Nuclear organization
Functional specificity in biomolecular condensates revealed by genetic complementation
Biomolecular condensates are thought to create subcellular microenvironments that regulate specific biochemical activities. Extensive in vitro work…
The maternal-to-zygotic transition: reprogramming of the cytoplasm and nucleus
A fertilized egg is initially transcriptionally silent and relies on maternally provided factors to initiate development. For embryonic development…