Tag: obesity
Association between early age body mass index and the risk of adulthood cardiovascular diseases: a systematic review and meta-analysis
Several studies have attempted to demonstrate the associations between body mass index (BMI) in early age and cardiovascular diseases (CVDs). Howev…
GRK5 is required for adipocyte differentiation through ERK activation
Previous studies have identified G protein-coupled receptor (GPCR) kinase 5 (GRK5) as a genetic factor contributing to obesity pathogenesis, but th…
Curcumin enhances the anti-obesogenic activity of orlistat through SKN-1/NRF2-dependent regulation of nutrient metabolism in Caenorhabditis elegans
Metabolic dysregulation, a defining feature of obesity, disrupts essential signalling pathways involved in nutrient sensing and mitochondria homeos…
Association of long-term weight management pharmacotherapy with multiple health outcomes: an umbrella review and evidence map
Multiple meta-analyses (MAs) have demonstrated that six pharmacotherapies, including orlistat, liraglutide, phentermine/topiramate, naltrexone/bupr…
Assessing online chat-based artificial intelligence models for weight loss recommendation appropriateness and bias in the presence of guideline incongruence
Managing obesity requires a comprehensive approach that involves therapeutic lifestyle changes, medications, or metabolic surgery. Many patients se…
Who drives weight stigma? A multinational exploration of clustering characteristics behind weight bias against preconception, pregnant, and postpartum women
Weight bias is a global health challenge and community members are endorsed as the most common source of weight bias. The nature of weight biases s…
Exploring the link between dietary inflammatory index, inflammatory biomarkers, and sleep quality in adults with obesity: a pilot investigation
Obesity is known to be associated with inflammation and impaired sleep quality. In addition, the anti-inflammatory properties of the daily diet pro…
Western diet since adolescence impairs brain functional hyperemia at adulthood in mice: rescue by a balanced ω-3:ω-6 polyunsaturated fatty acids ratio
Obesity is a devastating worldwide metabolic disease, with the highest prevalence in children and adolescents. Obesity impacts neuronal function bu…
Fasting appetite-related gut hormone responses after weight loss induced by calorie restriction, exercise, or both in people with overweight or obesity: a meta‐analysis
Altered appetite-related gut hormone concentrations may reflect a physiological adaptation facilitating weight regain after weight loss. This revie…