Tag: Personalized medicine
Diabetes in China: epidemiology, pathophysiology and multi-omics
Although diabetes is now a global epidemic, China has the highest number of affected people, presenting profound public health and socioeconomic ch…
Endothelial cell-related genetic variants identify LDL cholesterol-sensitive individuals who derive greater benefit from aggressive lipid lowering
The role of endothelial cell (EC) dysfunction in contributing to an individual’s susceptibility to coronary atherosclerosis and how low-density l…
Advancing clinical genomics with Middle Eastern and South Asian pangenomes
Migration, trade and climate The Middle East and South Asia form a contiguous landmass, historically serving as a bridge for migration, trade and cultural exchange,…
Evaluation of polygenic scores for hypertrophic cardiomyopathy in the general population and across clinical settings
Hypertrophic cardiomyopathy (HCM) is an important cause of morbidity and mortality, with pathogenic variants found in about a third of cases. Large…