Standardized workflow for multiplexed charge detection mass spectrometry on orbitrap analyzers
Individual ion mass spectrometry (I2MS) is the Orbitrap-based extension of the niche mass spectrometry technique known as charge detecti…
Tag: Proteomic analysis
PEPPI-MS: gel-based sample pre-fractionation for deep top-down and middle-down proteomics
Top-down analysis of intact proteins and middle-down analysis of proteins subjected to limited digestion require efficient detection of traces of p…
Biomarker analysis from complex biofluids by an on-chip chemically modified light-controlled vertical nanopillar array device
Nanostructured devices have proven useful in a broad range of applications, from diagnosing diseases to discovering and screening new drug molecule…
Sonication-assisted protein extraction improves proteomic detection of membrane-bound and DNA-binding proteins from tumor tissues
Deep-scale, mass spectrometry-based proteomic studies by the Clinical Proteomic Tumor Analysis Consortium (CPTAC) program involves tissue lysis usi…
Multiplexed spatial mapping of chromatin features, transcriptome and proteins in tissues
The phenotypic and functional states of cells are modulated by a complex interactive molecular hierarchy of multiple omics layers, involving the ge…
Cellular dsRNA interactome captured by K1 antibody reveals the regulatory map of exogenous RNA sensing
RNA-binding proteins (RBPs) provide a critical post-transcriptional regulatory layer in determining RNA fate. Currently, UV crosslinking followed b…