Body dysmorphic disorder
Body dysmorphic disorder (BDD) is an obsessive–compulsive disorder-related psychiatric condition characterized by an intense preoccupation with p…
Tag: Psychiatric disorders
Machine learning for identifying caregiving adversities associated with greatest risk for mental health problems in children
Developmental and experiential heterogeneity associated with caregiving-related early adversities (crEAs) poses a major challenge to identifying re…
Assessing well-being in clinical research and treatment
People with higher well-being fare better on important life outcomes from financial stability to mortality risk. Enhancing well-being is important …
An analysis on the role of glucagon-like peptide-1 receptor agonists in cognitive and mental health disorders
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are novel drugs approved for diabetes and obesity. They are acknowledged as a major scientific…
Divergent biological pathways linking short and long sleep durations to mental and physical health
Short and long sleep durations are associated with multiple physical, psychiatric and neurodegenerative diseases, yet their potentially shared and …
Transforming the evidence landscape in mental health with platform trials
Clinical trials are at the core of evidence-based medicine, but many are underpowered and fail to inform clinical practice. In mental health, the n…
Multiomic single-cell profiling identifies critical regulators of postnatal brain
Human brain development spans from embryogenesis to adulthood, with dynamic gene expression controlled by cell-type-specific cis-regulatory …
Comparison of the multivariate genetic architecture of eight major psychiatric disorders across sex
Differences in the patterning of genetic sharing between groups of individuals may arise from biological pathways, social mechanisms, phenotyping a…
Stress-induced changes in the molecular processes underlying fear memories: implications for PTSD and relevant animal models
Most of the fear literature on humans and animals tests healthy individuals. However, fear memories can differ between healthy individuals and thos…
Cognitive predictors of mental health trajectories are mediated by inferior frontal and occipital development during adolescence
Laboratory studies show brain maturation involves synaptic pruning and cognitive development. Human studies suggest links between early cognitive p…