Ectopic pregnancy
Ectopic pregnancy, defined as the implantation of a developing pregnancy outside of the endometrial cavity of the uterus, is the leading cause of e…
Tag: Reproductive disorders
Menopause-induced 17β-estradiol and progesterone loss increases senescence markers, matrix disassembly and degeneration in mouse cartilage
Female individuals who are post-menopausal present with higher incidence of knee osteoarthritis (KOA) than male counterparts; however, the mechanis…
Hydrops fetalis due to loss of function of hNav1.4 channel via compound heterozygous variants
Hydrops fetalis, characterized by abnormal fluid accumulation in fetuses, presents a significant risk of stillbirth and neonatal mortality. Althoug…
Placental nanoparticle-mediated IGF1 gene therapy corrects fetal growth restriction in a guinea pig model
Fetal growth restriction (FGR) caused by placental insufficiency is a major contributor to neonatal morbidity and mortality. There is currently no …
Macrophages: a double-edged sword in female reproduction and disorders
Reproduction consists of sequential inflammation-like events, primarily within the endometrium, from ovulation to embryo implantation, decidualizat…
Re-reply to Sabbagh et al.
To the Editor: We thank you for giving us the opportunity to respond to the reply of Sabbagh et al. [1] on our correspondence [2],…
Endothelial senescence induced by PAI-1 promotes endometrial fibrosis
Intrauterine adhesions (IUAs), also known as Asherman’s syndrome (AS), represent a significant cause of uterine infertility for which effective t…
Inhibition of ferroptosis counteracts the advanced maternal age-induced oocyte deterioration
Ferroptosis, a recently discovered form of programmed cell death triggered by the excessive accumulation of iron-dependent lipid peroxidation produ…