Rolling toward circular solutions
Tag: RNA splicing
Non-viral intron knock-ins for targeted gene integration into human T cells and for T-cell selection
Current methods for the precise integration of DNA sequences into the genome of human T cells predominantly target exonic regions, which limits the…
Molecular basis of myelodysplastic syndromes
Myelodysplastic syndromes (MDS) are myeloid neoplasms characterized by dysplasia in one or more cell lines, ineffective hematopoiesis and variable …
RBPMS inhibits bladder cancer metastasis by downregulating MYC pathway through alternative splicing of ANKRD10
RNA-binding proteins (RBPs) are pivotal mediators of the alternative splicing (AS) machinery of pre-mRNA. Research has demonstrated that the AS pro…
The potential impact of RNA splicing abnormalities on immune regulation in endometrial cancer
RNA splicing controls the post-transcriptional level of gene expression, allowing for the synthesis of many transcripts with various configurations…