Profiling the total transcriptome of single nuclei in archived samples with snRandom-seq
Tag: Sequencing
Vector choices, vector surprises
Not all plasmids are fine Last year, the VectorBuilder team and colleagues published a preprint6 that set off some alarm bells about plasmids. They called…
A novel missense pathogenic variants of TMEM53 in an Iranian family with craniotubular dysplasia, Ikegawa type
Craniotubular dysplasia, Ikegawa type (CTDI) is a rare autosomal recessive skeletal dysplasia characterized by hyperostosis of the calvaria and sku…
Analysis of microbial composition and sharing in low-biomass human milk samples: a comparison of DNA isolation and sequencing techniques
Human milk microbiome studies are currently hindered by low milk bacterial/human cell ratios and often rely on 16S rRNA gene sequencing, which limi…
The shared role of neutrophils in ankylosing spondylitis and ulcerative colitis
This study aimed to analyze single-cell sequencing data to investigate immune cell interactions in ankylosing spondylitis (AS) and ulcerative colit…
Predictable regulation of gut microbiome in immunotherapeutic efficacy of gastric cancer
Immunotherapy has showcased remarkable progress in the management of gastric cancer (GC), prompting the need to proactively identify and classify p…