Reproducible image-based profiling with Pycytominer
Advances in high-throughput microscopy have enabled the rapid acquisition of large numbers of high-content microscopy images. Next, whether by deep…
Tag: Software
DREDge: robust motion correction for high-density extracellular recordings across species
High-density microelectrode arrays have opened new possibilities for systems neuroscience, but brain motion relative to the array poses challenges …
Spotiphy enables single-cell spatial whole transcriptomics across an entire section
Spatial transcriptomics (ST) has advanced our understanding of tissue regionalization by enabling the visualization of gene expression within whole…
Evolutionary optimization of model merging recipes
Large language models (LLMs) have become increasingly capable, but their development often requires substantial computational resources. Although m…
ImmuneLENS characterizes systemic immune dysregulation in aging and cancer
Recognition and elimination of pathogens and cancer cells depend on the adaptive immune system. Thus, accurate quantification of immune subsets is …
Secure and federated genome-wide association studies for biobank-scale datasets
Sharing data across institutions for genome-wide association studies (GWAS) would enhance the discovery of genetic variation linked to health and d…
Spatial modeling algorithms for reactions and transport in biological cells
Biological cells rely on precise spatiotemporal coordination of biochemical reactions to control their functions. Such cell signaling networks have…