Opportunities and limitations of B cell depletion approaches in SLE
B cell depletion with rituximab, a chimeric monoclonal antibody that selectively targets B cells by binding CD20, has been used off label in sever…
Tag: Systemic lupus erythematosus
Dysregulation in keratinocytes drives systemic lupus erythematosus onset
Systemic lupus erythematosus (SLE) is a complex, multiorgan autoimmune disorder. Although it is widely believed that SLE originates from immune cel…