Cross-priming in cancer immunology and immunotherapy
Cytotoxic T cell immune responses against cancer crucially depend on the ability of a subtype of professional antigen-presenting cells termed conve…
Tag: Tumour vaccines
Small circular RNAs as vaccines for cancer immunotherapy
Messenger RNA vaccines have shown strong prophylactic efficacy against viral infections. Here we show that antigen-encoding small circular RNAs (ci…
Sequential STING and CD40 agonism drives massive expansion of tumor-specific T cells in liposomal peptide vaccines
The clinical use of cancer vaccines is hampered by the low magnitude of induced T-cell responses and the need for repetitive antigen stimulation. H…