T cell-mediated protection in absence of virus neutralizing antibodies
Tag: Vaccines
PROTAR Vaccine 2.0 generates influenza vaccines by degrading multiple viral proteins
Manipulating viral protein stability using the cellular ubiquitin-proteasome system (UPS) represents a promising approach for developing live-atten…
Potent prophylactic cancer vaccines harnessing surface antigens shared by tumour cells and induced pluripotent stem cells
The development of prophylactic cancer vaccines typically involves the selection of combinations of tumour-associated antigens, tumour-specific ant…
The antitumor activity of TGFβ-specific T cells is dependent on IL-6 signaling
Although interleukin (IL)-6 is considered immunosuppressive and tumor-promoting, emerging evidence suggests that it may support antitumor immunity.…