In vitro and in vivo characterization of a novel West Nile virus lineage 2 strain
Over recent decades, West Nile virus (WNV) has continued to expand its geographical range, emerging in previously non-endemic areas, including nort…
Tag: Viral pathogenesis
Genotoxic consequences of viral infections
Viral diseases continually threaten human health as evolving pathogens introduce new risks. These infections can lead to complications across organ…
Dose and strain dependent lethality of Usutu virus in an Ifnar−/− mouse model
Usutu virus (USUV) is a mosquito-borne zoonotic flavivirus with a geographic range that has expanded over recent years. Maintained in a transmissio…
Pathogenesis of aquatic bird bornavirus 1 in turkeys of different age
Aquatic bird bornavirus 1 (ABBV1), an orthobornavirus in the family Bornaviridae, displays a broad host range among avian species, including…
Host genetic diversity contributes to disease outcome in Crimean-Congo hemorrhagic fever virus infection
The Crimean-Congo hemorrhagic fever virus (CCHFV) causes Crimean-Congo hemorrhagic fever (CCHF), a widely distributed disease with significant morb…
The consequences of SARS-CoV-2 within-host persistence
SARS-CoV-2 causes an acute respiratory tract infection that resolves in most people in less than a month. Yet some people with severely weakened im…